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Peptide record

TPDB92510

Lyp-1 Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92510
Lyp-1
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
CGNKRTRGC-NH2
Physicochemical Analysis
C36H67N17O12S2
ADEQHILMFPSWYV
RCG
994.15
10.12
3
0
0
+3
2.71
-1.433
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.57
4
Residue Composition
number
0
A
2
R
1
N
0
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C36H67N17O12S2
994.15
10.12
+3
2.71
-1.433
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MDA-MB-435 cells

Source & Reference

CPPsite3.0
CPPsite3
US 7192921

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (fluorescein)
Cytoplasm and nucleus
In vitro
CCCCTTTTC
Additional Detail Fields 1 fields
CCCCTTTTC