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Peptide record

TPDB92508

CLT1 Anticancer Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB92508
CLT1
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 10-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: Cy5 labeling
Sequence
CGLIIQKNEC
Physicochemical Analysis
C46H81N13O15S2
ARDHMFPSTWYV
CI
1120.35
6.14
1
1
3
-0
2.36
0.300
117.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
11.16
4
Residue Composition
number
0
A
0
R
1
N
0
D
2
C
1
E
1
Q
1
G
0
H
2
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 2 E: 1 Q: 1 G: 1 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C46H81N13O15S2
1120.35
6.14
-0
2.36
0.300
Cy5 labeling
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Fibrillar meshwork in the extracellular compartment of the tumors
Homing
Prostate cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
MR molecular imaging of prostate cancer with a peptide-targeted contrast agent in a mouse orthotopic prostate cancer model
2011
Tan M et al. Pharma Res 2011 Dec 3.
US 2009/021442A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
PC-3 human prostate adenocarcinoma cells
Athymic male nude mice
Synthetic
Gadolinium-tetraazacyclododecanetetraacetic acid (Gd-DOTA) complex
Additional Detail Fields 3 fields
Gadolinium-tetraazacyclododecanetetraacetic acid (Gd-DOTA) complex
PC-3 human prostate adenocarcinoma cells
Athymic male nude mice