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Peptide record

TPDB92504

CM–FA Anticancer Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB92504
CM–FA
Anticancer Cell-penetrating Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CancerPPD 2.0 CPPsite3.0
standard
No
A 27-aa standard natural multi-activity (Anticancer and Cell-penetrating Peptides) peptide sequence curated from CancerPPD 2.0 and CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Folic Acid
Sequence
CGIGAVLKVLTTGLPALISWIKRKRQQ-NH2
Physicochemical Analysis
C134H233N39O33S1
NDEHMFY
L
2950.63
11.56
5
0
12
+5
1.18
0.356
130.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5500
186.40
6
Residue Composition
number
2
A
2
R
0
N
0
D
1
C
0
E
2
Q
3
G
0
H
3
I
4
L
3
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 2 G: 3 H: 0 I: 3 L: 4 K: 3 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
27
C134H233N39O33S1
2950.63
11.56
+5
1.18
0.356
Amidation
L
Linear
Folic Acid
Anticancer Antibacterial
Synthetic analogue
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 67.34 µg/mL
Anticancer
67.34 µg/mL

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 35.75 µg/mL
Anticancer
35.75 µg/mL

Target

Cervical Cancer
C-33A
Cervix

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
Evidence 3 Activity

Activity

IC50
IC50 = 10.38 µg/mL
Anticancer
10.38 µg/mL

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023