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Peptide record

TPDB92499

RGD Cell-penetrating Peptides Toxicity Tumor-homing Peptides standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB92499
RGD
Cell-penetrating Peptides Toxicity Tumor-homing Peptides
Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia TumorHoPe2.0
standard
No
A 3-aa standard natural multi-activity (Cell-penetrating Peptides, Toxicity, and Tumor-homing Peptides) peptide sequence curated from CPPsite3.0, Peptipedia, and TumorHoPe2.0, with an available 3D structural model.
Chemical: PLGA nanoparticles
Sequence
RGD
Physicochemical Analysis
C12H22N6O6
ANCEQHILKMFPSTWYV
RDG
346.34
6.78
1
1
0
-0
2.05
-2.800
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C12H22N6O6
346.34
6.78
-0
2.05
-2.800
Free
PLGA nanoparticles
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human Tongue Squamous Cell Carcinoma Cell Lines (Cal-27)

Assay & Model

Female BALB/c Nude mice
Female BALB/c Nude mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Verteporfin (Ver)
Enhanced the cellular uptake of Ver
In vitro and in vivo
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC