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Peptide record

TPDB92466

Rev (34-50) Antibacterial Antiviral Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB92466
Rev (34-50)
Antibacterial Antiviral Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0 CellPPD CPPsite3.0 PerseuCPP
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antiviral, and Cell-penetrating Peptides) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
C-terminal: Conjugation with fluorescein by C-terminal Cys amide
Sequence
TRQARRNRRRRWRERQR
Physicochemical Analysis
C97H173N51O24
DCGHILKMFPSYV
R
2437.77
13.00
10
1
2
+9
9.82
-3.459
5.88
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
5500
225.62
4
Residue Composition
number
1
A
10
R
1
N
0
D
0
C
1
E
2
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 10 N: 1 D: 0 C: 0 E: 1 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C97H173N51O24
2437.77
13.00
+9
9.82
-3.459
Conjugation with fluorescein by C-terminal Cys amide
L
Cationic
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

RAW 264.7

Source & Reference

CPPsite3.0
CPPsite3
US 20060223752

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (fluorescein)
Cytoplasm and nucleus
High (comparable to Tat (48-60)
Non-endocytic mechanism
In vitro
CCCCTTTHHHHHHHTCC
Additional Detail Fields 1 fields
CCCCTTTHHHHHHHTCC