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Peptide record

TPDB92462

[RW]3 Antibacterial Anticancer Antifungal Antiviral Cell-penetrating Peptides Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB92462
[RW]3
Antibacterial Anticancer Antifungal Antiviral Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
Peptipedia AntiCP 2.0 iACP-DRLF CAFPdb DRAMP dbAMP CPPsite3.0
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, iACP-DRLF, and other sources, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
RWRWRW
Physicochemical Analysis
C51H68N18O7
ANDCEQGHILKMFPSTYV
RW
1045.22
12.70
3
0
3
+3
-3.12
-2.700
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
1578.62
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
6
C51H68N18O7
1045.22
12.70
+3
-3.12
-2.700
Free
L
Amphiphilic
Linear
Conjugated with FITC
N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Synthetic
Gemcitabine (Gem) and FITC dye
Nucleus
Maximum intracellular fluorescence relative to other peptides
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC