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Peptide record

TPDB92447

V2 V2R Antibacterial Anticancer Antiviral Cell-penetrating Peptides Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB92447
V2 V2R
Antibacterial Anticancer Antiviral Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
Peptipedia dbAMP 3.0 CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, CellPPD, and other sources, with an available 3D structural model.
C-terminal: Amidation Chemical: β-alanine–glycine–glycine linker N-terminal: Conjugated with FITC via AβGG Linker
Sequence
RRRRRR-NH2
Physicochemical Analysis
C36H74N24O7
ANDCEQGHILKMFPSTWYV
R
955.14
13.10
6
0
0
+6
4.86
-4.500
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C36H74N24O7
955.14
13.10
+6
4.86
-4.500
Amidation
β-alanine–glycine–glycine linker
L
Linear
Conjugated with FITC via AβGG Linker
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Nih-3T3 Swiss Mice Fibroblasts And Jurkat E6 Human Leukemia Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
FITC dye
Cytoplasm and nucleus
Stronger preference to accumulate within the nuclear bodies
In vitro
CCCGGGGGTTGGGGCCCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Nih-3T3 Swiss Mice Fibroblasts And Jurkat E6 Human Leukemia Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
Synthetic
FITC dye
Lack of cellular uptake
In vitro
CCCGGGGGTTTHHHHCCC
Additional Detail Fields 1 fields
CCCGGGGGTTGGGGCCCC CCCGGGGGTTTHHHHCCC