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Peptide record

TPDB92428

Cyclosaplin Antibacterial Anticancer Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB92428
Cyclosaplin
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0 SATPdb dbACP ToxinPred 3.0
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, CancerPPD 2.0, SATPdb, and other sources, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
RLGDGCTR
Physicochemical Analysis
C33H60N14O12S1
ANEQHIKMFPSWYV
RG
876.99
9.01
2
1
1
+1
2.21
-0.963
48.75
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
1
D
1
C
0
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C33H60N14O12S1
876.99
9.01
+1
2.21
-0.963
Cyclized
L
Cyclic
Cyclized
Anticancer
Santalum album L
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 2.06 µg/mL
Anticancer
2.06 µg/mL

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2014
638/KOL/2013

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.