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Peptide record

TPDB92425

cRGD Antibacterial Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB92425
cRGD
Antibacterial Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD-MOD CPPsite3.0 PerseuCPP TumorHoPe2.0
standard
No
A 5-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from Peptipedia, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: FITC fluorescent probe
Sequence
RGDFK
Physicochemical Analysis
C27H43N9O8
ANCEQHILMPSTWYV
RDGKF
621.69
10.09
2
1
1
+1
1.91
-1.900
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C27H43N9O8
621.69
10.09
+1
1.91
-1.900
FITC fluorescent probe
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Lung cancer, Breast cancer, Oral cancer, esophageal cancer
αvβ3 integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
New-generation photosensitizer-anchored gold nanorods for a single near-infrared light-triggered targeted photodynamic-photothermal therapy
2021
Zongjunlin Liu et al. Drug Deliv. 2021 Dec 28(1):1769-1784.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
esophageal cancer cells (ECA109)
female BALB/c mice (4–5weeks of age, 18–20g)
Synthetic
chlorin e6-C-15-ethyl ester
Cyclic
Additional Detail Fields 3 fields
chlorin e6-C-15-ethyl ester
esophageal cancer cells (ECA109)
female BALB/c mice (4–5weeks of age, 18–20g)