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Peptide record

TPDB92404

Peptide 7b Antibacterial Anticancer Antifungal standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB92404
Peptide 7b
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0
standard
No
A 2-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
N-terminal: 4-azidobenzoic acid
Sequence
PD
Physicochemical Analysis
C9H14N2O5
ARNCEQGHILKMFSTWYV
DP
230.22
3.10
0
1
0
-1
1.68
-2.550
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C9H14N2O5
230.22
3.10
-1
1.68
-2.550
Free
L
Linear
4-azidobenzoic acid
Antiproliferative, Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 19.1 ± 0.04 µM
Anticancer
19.1

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 21.8 ± 0.03 µM
Anticancer
21.8

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
Evidence 3 Activity

Activity

IC50
IC50 = 17.9 ± 0.02 µM
Anticancer
17.9

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017