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Peptide record

TPDB92381

Dex-(KW)3 Antibacterial Anticancer Antifungal Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB92381
Dex-(KW)3
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF CAFPdb DRAMP dbAMP
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation Chemical: Dextran N-terminal: Dextran
Sequence
KWKWKW-NH2
Physicochemical Analysis
C51H68N12O7
ARNDCEQGHILMFPSTYV
KW
961.18
10.84
3
0
3
+3
-2.58
-2.400
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
1716.64
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
6
C51H68N12O7
961.18
10.84
+3
-2.58
-2.400
Amidation
Dextran
L
Linear
Dextran
Anticancer
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

at 10 µM 60% viablity
Anticancer

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2010

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

at 10 µM 35-40% viablity
Anticancer

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2010