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Peptide record

TPDB92351

Si7 Antibacterial Anticancer Antifungal Toxicity Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB92351
Si7
Antibacterial Anticancer Antifungal Toxicity Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AntiCP 2.0 CancerPPD 2.0 iACP-DRLF TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: 1,8-naphthalimide-Gly
Sequence
KLAKLAK-NH2
Physicochemical Analysis
C36H70N10O8
RNDCEQGHIMFPSTWYV
K
771.01
10.84
3
0
4
+3
1.51
-0.071
140.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C36H70N10O8
771.01
10.84
+3
1.51
-0.071
Amidation
L
Linear
1,8-naphthalimide-Gly
Antimicrobial and Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 1195 ± 131.5 µM
Anticancer
1195

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.