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Peptide record

TPDB92345

B7 Antibacterial Anticancer Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB92345
B7
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKLFKKILKY-NH2
Physicochemical Analysis
C66H113N15O12
ARNDCEQGHMPSTWV
K
1308.72
10.77
5
0
5
+5
1.45
-0.590
117.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
113.85
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C66H113N15O12
1308.72
10.77
+5
1.45
-0.590
Amidation
L
Linear
Free
Antimicrobial
Analogue of BP 100
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 73.7 ± 6.1 µM
Anticancer
73.7

Target

Leukemia Cancer
K-562
Blood

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 77.3 ± 5.6 µM
Anticancer
77.3

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
Evidence 3 Activity

Activity

IC50
IC50 = 97.3 ± 11.4 µM
Anticancer
97.3

Target

Breast Cancer
MCF-7/ADM
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017