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Peptide record

TPDB92325

Picturin 2BN Antibacterial Anticancer standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB92325
Picturin 2BN
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0 dbACP
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia, CancerPPD 2.0, and dbACP, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLMDMLKKVGKVALTVAKSALLP-NH2
Physicochemical Analysis
C108H195N27O28S2
RNCEQHIFWY
L
2384.02
10.55
4
1
13
+3
2.37
0.774
135.65
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
0
I
5
L
4
K
2
M
0
F
1
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 5 K: 4 M: 2 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
23
C108H195N27O28S2
2384.02
10.55
+3
2.37
0.774
Amidation
L
Linear
Free
Antimicrobial and Antitumor
Giant Gladiator Treefrog (Boana boans)
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
LC50 = 23 µM
Anticancer
23 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

LC50
LC50 26.3 uM
Anticancer
26.3 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023
Evidence 3 Activity

Activity

LC50
LC50 52.2 uM
Anticancer
52.2 µM

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023