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Peptide record

TPDB92320

Picturin 1BN Antibacterial Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB92320
Picturin 1BN
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0 dbACP
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia, CancerPPD 2.0, and dbACP, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIFKDTLKKVVAAVLTTVADNIHPK-NH2
Physicochemical Analysis
C123H208N32O34
RCEQMSWY
KV
2679.20
10.16
5
2
12
+2
5.58
0.328
120.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
3
A
0
R
1
N
2
D
0
C
0
E
0
Q
1
G
1
H
2
I
2
L
4
K
0
M
1
F
1
P
0
S
3
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 4 M: 0 F: 1 P: 1 S: 0 T: 3 W: 0 Y: 0 V: 4
Chemical Descriptors
25
C123H208N32O34
2679.20
10.16
+2
5.58
0.328
Amidation
L
Linear Linaer
Free
Antimicrobial and Antitumor
Giant Gladiator Treefrog (Boana boans)
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
LC50 = 30.7 µM
Anticancer
30.7 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

LC50
LC50 = 64.2 uM
Anticancer
64.2 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023
Evidence 3 Activity

Activity

LC50
LC50 = 84.9 uM
Anticancer
84.9 µM

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023