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Peptide record

TPDB92308

R-DIM-P-LF11-215 Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB92308
R-DIM-P-LF11-215
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FWRIRIRRPRRIRIRWF-NH2
Physicochemical Analysis
C117H187N43O18
ANDCEQGHLKMSTYV
R
2484.05
13.25
8
0
8
+8
-0.27
-0.929
91.76
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
442.83
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
4
I
0
L
0
K
0
M
2
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 0 K: 0 M: 0 F: 2 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
17
C117H187N43O18
2484.05
13.25
+8
-0.27
-0.929
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
LC50 = 2.7 ± 0.9 µM
Anticancer
2.7

Target

Skin Cancer
A-375
Skin

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
EP_2943215_B1

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

LC50
LC50 < 1 ± 0.0 µM
Anticancer
1

Target

Skin Cancer
SBcl2
Skin

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
EP_2943215_B1
Evidence 3 Activity

Activity

LC50
LC50 = 4.6 ± 0.1 µM
Anticancer
4.6

Target

Skin Cancer
WM164
Skin

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
EP_2943215_B1