Back to search

Peptide record

TPDB92304

Longicalycinin A cyclic analogue 17 Antibacterial Anticancer Toxicity standard
5 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92304
Longicalycinin A cyclic analogue 17
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0
standard
No
A 5-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
FSPFA
Physicochemical Analysis
C29H37N5O7
RNDCEQGHILKMTWYV
F
567.64
6.02
0
0
3
-0
-1.85
1.000
20.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C29H37N5O7
567.64
6.02
-0
-1.85
1.000
Cyclized
L
Cyclic
Cyclized
Anticancer
Synthetic Analogue of Longicalycinin A
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
IC50 = 9.4 ± 0.0014 µg/ml
Anticancer
9.4

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 11.2 ± 0.0007 µg/ml
Anticancer
11.2

Target

Colorectal Cancer
HT-29
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
Evidence 3 Activity

Activity

74.53% Cell death at 100 µg/ml
Anticancer

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
Evidence 4 Activity

Activity

76.14% Cell death at 100 µg/ml
Anticancer

Target

Colorectal Cancer
HT-29
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020