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Peptide record

TPDB92301

R-DIM-P-LF11 Antibacterial Anticancer Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB92301
R-DIM-P-LF11
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FQWQRNIRKVRPRVKRINRQWQF-NH2
Physicochemical Analysis
C143H227N51O30
ADCEGHLMSTY
R
3140.70
13.10
8
0
8
+8
4.01
-1.574
59.13
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
350.24
6
Residue Composition
number
0
A
6
R
2
N
0
D
0
C
0
E
4
Q
0
G
0
H
2
I
0
L
2
K
0
M
2
F
1
P
0
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 2 D: 0 C: 0 E: 0 Q: 4 G: 0 H: 0 I: 2 L: 0 K: 2 M: 0 F: 2 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
23
C143H227N51O30
3140.70
13.10
+8
4.01
-1.574
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
LC50 = 125.0 ± 16.8 µM
Anticancer
125.0

Target

Skin Cancer
A-375
Skin

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
EP_2943215_B1

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

LC50
LC50 = 10.7 ± 0.2 µM
Anticancer
10.7

Target

Skin Cancer
SBcl2
Skin

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
EP_2943215_B1
Evidence 3 Activity

Activity

LC50
LC50 = 20.9 ± 3.9 µM
Anticancer
20.9

Target

Skin Cancer
WM164
Skin

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
EP_2943215_B1