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Peptide record

TPDB92296

B1AW-K Antibacterial Anticancer Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB92296
B1AW-K
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0 dbACP Hemolytic2
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CancerPPD 2.0, dbACP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLPLLAGLAANFLPKIICKIARKC-NH2
Physicochemical Analysis
C124H209N31O26S2
DEQHMSTWYV
L
2614.34
10.32
4
0
14
+4
-2.04
1.125
146.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.78
3
Residue Composition
number
4
A
1
R
1
N
0
D
2
C
0
E
0
Q
1
G
0
H
3
I
5
L
3
K
0
M
2
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 5 K: 3 M: 0 F: 2 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C124H209N31O26S2
2614.34
10.32
+4
-2.04
1.125
Amidation
L
Linear
Free
Antimicrobial and Antitumor
analogue of B1AW
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 4.283 µM
Anticancer
4.283 µM

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 5.15 µM
Anticancer
5.15 µM

Target

Lung Cancer
H-838
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023
Evidence 3 Activity

Activity

IC50
IC50 = 3.860 µM
Anticancer
3.860 µM

Target

Brain Tumor
U251-MG
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2023