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Peptide record

TPDB92293

Antibacterial Toxicity modified_plain modified
23 amino acids
Basic Information
3D PDB MODEL
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TPDB92293
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 23-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
FIXKFAKXFKXFIXKFAKFAFAF
Physicochemical Analysis
C126H176N24O20
RNDCEQGHLMPSTWYV
F
2346.93
11.12
5
0
14
+5
-5.39
0.830
51.30
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
5
K
0
M
8
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 5 M: 0 F: 8 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C126H176N24O20
2346.93
11.12
+5
-5.39
0.830
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
34.3 µg/mL
Cytotoxic
50% Cell death | 34.3 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Designed Antimicrobial Peptides for Topical Treatment of Antibiotic Resistant Acne Vulgaris. | Antibiotics (Basel) | 2020