Back to search

Peptide record

TPDB92275

Gageostatin C Antibacterial Anticancer Antifungal Antiviral Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92275
Gageostatin C
Antibacterial Anticancer Antifungal Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0 dbACP CAFPdb dbAMP
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CancerPPD 2.0, dbACP, and other sources, with an available 3D structural model.
N-terminal: (E)-7,9-dimethylundec-2-enoic acid
Sequence
ELLVDLL
Physicochemical Analysis
C38H67N7O12
ARNCQGHIKMFPSTWY
L
813.99
3.01
0
2
5
-2
1.08
1.771
264.29
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
1
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C38H67N7O12
813.99
3.01
-2
1.08
1.771
Free
L
Linear
(E)-7,9-dimethylundec-2-enoic acid
Antimicrobial
Bacillus subtilis
Evidence Records 6 records
Evidence 1 Activity

Activity

GI50
GI50 = 11.2 µg/mL
Anticancer
11.2 µg/mL

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2014

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

GI50
GI50 = 23.2 µg/mL
Anticancer
23.2 µg/mL

Target

Colon Cancer
HCT-15
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2014
Evidence 3 Activity

Activity

GI50
GI50 = 11.7 µg/mL
Anticancer
11.7 µg/mL

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2014
Evidence 4 Activity

Activity

GI50
GI50 = 10.9 µg/mL
Anticancer
10.9 µg/mL

Target

Lung Cancer
NCI-H23
Lung

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2014
Evidence 5 Activity

Activity

GI50
GI50 = 10.5 µg/mL
Anticancer
10.5 µg/mL

Target

Stomach Cancer
NUGC-3
Stomach

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2014
Evidence 6 Activity

Activity

GI50
GI50 = 12.3 µg/mL
Anticancer
12.3 µg/mL

Target

Renal Cancer
ACHN
Kidney

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2014