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Peptide record

TPDB92271

Antibacterial Anticancer Blood-Brain Barrier Cell-penetrating Peptides Toxicity Tumor-homing Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB92271
Antibacterial Anticancer Blood-Brain Barrier Cell-penetrating Peptides Toxicity Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
Peptipedia BBPpredict CPPsite3.0 StackTHP StackTHPred TumorHoPe2.0
standard
No
A 5-aa standard natural multi-activity (Antibacterial, Anticancer, Blood-Brain Barrier, and other sources) peptide sequence curated from Peptipedia, BBPpredict, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Cys
Sequence
CREKA
Physicochemical Analysis
C23H43N9O8S1
NDQGHILMFPSTWYV
ARCEK
605.71
8.97
2
1
1
+1
3.41
-1.520
20.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
1
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C23H43N9O8S1
605.71
8.97
+1
3.41
-1.520
Cys
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Homing
Breast cancer
fibronectin

Source & Reference

TumorHoPe2.0
TumorHoPe2
SREKA-targeted liposomes for highly metastatic breast cancer therapy
2023
Balázs Vári et al. Drug Deliv. 2023 Feb 8 30(1):2174210.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
4T1-Luc triple-negative murine breast cancer, NIH-3T3 cell line
8- to 12-week-old female Balb/c mice
Phage Display Library
DSPE-PEGs
Additional Detail Fields 3 fields
DSPE-PEGs
4T1-Luc triple-negative murine breast cancer, NIH-3T3 cell line
8- to 12-week-old female Balb/c mice