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Peptide record

TPDB92267

CI-15 Antibacterial Anticancer Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB92267
CI-15
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
CIIKKIIKKIIKKII-NH2
Physicochemical Analysis
C87H167N21O16S1
ARNDEQGHLMFPSTWYV
I
1795.47
10.82
6
0
8
+6
3.22
1.007
208.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
8
I
0
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 8 L: 0 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C87H167N21O16S1
1795.47
10.82
+6
3.22
1.007
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 7.7 ± 0.2 µM
Anticancer
7.7

Target

Colorectal Cancer
HCT-116
Colon

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 2.7 ± 0.5 µM
Anticancer
2.7

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022