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Peptide record

TPDB92263

Mut-LDP-NLS Antibacterial Antifungal Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB92263
Mut-LDP-NLS
Antibacterial Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
Peptipedia Antifungipept CAFPdb dbAMP CPPsite3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, and Cell-penetrating Peptides) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
AWRRKLKALAPAKKAKV
Physicochemical Analysis
C90H159N29O18
NDCEQGHIMFSTY
AK
1935.44
12.45
7
0
9
+7
3.27
-0.600
92.35
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
284.17
0
Residue Composition
number
5
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
5
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 5 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
17
C90H159N29O18
1935.44
12.45
+7
3.27
-0.600
Free
L
Linear
Conjugated with FITC
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
β-galactosidase
Did not exhibit cellular fluorescence
In vitro
CCCCCCCSCTTSCCCGGGGGSCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Fusarium Solani

Source & Reference

CPPsite3.0
CPPsite3

Other

Non-natural residues Linear L
Synthetic
FITC dye
Showed significantly lesser uptake than LDP-NLS
In vitro
Additional Detail Fields 1 fields
CCCCCCCSCTTSCCCGGGGGSCC