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Peptide record

TPDB92262

Dermaseptin-TO Antibacterial Anticancer Antifungal Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB92262
Dermaseptin-TO
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0 CAFPdb ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CancerPPD 2.0, CAFPdb, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
ALWKDLLKNVGIAAGKAALNKVTDMVNQ-NH2
Physicochemical Analysis
C133H225N37O38S1
RCEHFPSY
A
2982.53
10.16
4
2
15
+2
3.15
0.150
118.57
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
184.41
5
Residue Composition
number
5
A
0
R
3
N
2
D
0
C
0
E
1
Q
2
G
0
H
1
I
4
L
4
K
1
M
0
F
0
P
0
S
1
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 5 R: 0 N: 3 D: 2 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 4 K: 4 M: 1 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 3
Chemical Descriptors
28
C133H225N37O38S1
2982.53
10.16
+2
3.15
0.150
Amidation
L
Linear
Free
Antimicrobial
Phyllomedusa tomopterna
Evidence Records 3 records
Evidence 1 Activity

Activity

Graph Figure-7
Anticancer

Target

Brain Tumor
U251-MG
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Graph Figure-7
Anticancer

Target

Lung Cancer
H-157
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 3 Activity

Activity

Graph Figure-7
Anticancer

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021