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Peptide record

TPDB92250

MAD1 Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB92250
MAD1
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia CancerPPD 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
KRWHWWRRHWVVW-NH2
Physicochemical Analysis
C101H132N32O14
ANDCEQGILMFPSTY
W
2018.37
12.71
6
0
7
+4
-3.77
-1.531
44.62
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
27500
1362.49
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
2
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 2 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 2
Chemical Descriptors
13
C101H132N32O14
2018.37
12.71
+4
-3.77
-1.531
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 14.2 µM
Anticancer
14.2 µM

Target

Ovarian Cancer
OVCAR-3
Ovary

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
US11571454 B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 36.2 µM
Anticancer
36.2 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
US11571454 B2
Evidence 3 Activity

Activity

IC50
IC50 = 85.6 µM
Anticancer
85.6 µM

Target

Ovarian Cancer
NCI/ADR-RES
Ovary

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
US11571454 B2