Back to search

Peptide record

TPDB92189

Phylloseptin-PBa3 Antibacterial Anticancer Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92189
Phylloseptin-PBa3
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLSLIPHIVSGVAALANHL-NH2
Physicochemical Analysis
C93H150N24O23
RDCEQKMTWY
L
1972.36
8.00
2
0
12
+0
-1.30
1.437
169.47
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
2
H
2
I
4
L
0
K
0
M
1
F
1
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 2 I: 2 L: 4 K: 0 M: 0 F: 1 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
19
C93H150N24O23
1972.36
8.00
+0
-1.30
1.437
Amidation
L
Linear
Free
Antimicrobial
Phyllomedusa burmeisteri
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 208 µM
Anticancer
208 µM

Target

Breast Cancer
MDA-MB-435S
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Cell viability
Cell viability ~ 65% at 10-5 M
Anticancer
~65 % at 10-5 M

Target

Lung Cancer
H-838
Lung

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019