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Peptide record

TPDB92178

Pep-1 Antibacterial Anticancer Cell-penetrating Peptides Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB92178
Pep-1
Antibacterial Anticancer Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0 PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIKKFLKSAKKFVKAFK-NH2
Physicochemical Analysis
C97H162N24O19
RNDCEQHMPTWY
K
1968.50
11.29
7
0
8
+7
2.54
-0.235
74.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
7
K
0
M
3
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 7 M: 0 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C97H162N24O19
1968.50
11.29
+7
2.54
-0.235
Amidation
L
Linear
Free
NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa And Huh-7-Luc Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Cy5-plasmid DNA , mRNA , siRNA
Cytoplasm
In vitro
CHHHHCSTHHHHGGGGTTTTTC
Additional Detail Fields 1 fields
CHHHHCSTHHHHGGGGTTTTTC