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Peptide record

TPDB92142

pAntp (46-58) Antibacterial Anticancer Cell-penetrating Peptides Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB92142
pAntp (46-58)
Antibacterial Anticancer Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation (Labeled with Biotinyl-beta-Alanine)
Sequence
KIWFQNRRMKWKK-NH2
Physicochemical Analysis
C87H137N27O16S1
ADCEGHLPSTYV
K
1849.28
12.44
6
0
5
+6
1.21
-1.862
30.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
594.83
2
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
0
L
4
K
1
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 4 M: 1 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
13
C87H137N27O16S1
1849.28
12.44
+6
1.21
-1.862
Amidation
L
Amphipathic
Linear
Biotinylation (Labeled with Biotinyl-beta-Alanine)
N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HaCat/ A549 cells

Source & Reference

CPPsite3.0
CPPsite3
US 7153931

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Biotin
Probably Cytosol and nucleus, nucleoi
Medium (65% relative to (pAntp) (43-58))
Non-endocytic mechanism
In vitro
CCCCCSCCCCCCC
Additional Detail Fields 1 fields
CCCCCSCCCCCCC