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Peptide record

TPDB92136

[Arg]11-VmCT1 Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB92136
[Arg]11-VmCT1
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CancerPPD 2.0 Antifungipept CAFPdb PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLGALWNVAKRVF-NH2
Physicochemical Analysis
C75H113N19O15
DCEQHIMPSTY
ALFV
1520.84
11.49
2
0
9
+2
-3.20
0.923
120.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
361.64
1
Residue Composition
number
2
A
1
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
1
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 1 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
13
C75H113N19O15
1520.84
11.49
+2
-3.20
0.923
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 25.8 ± 5.2 µmol/L
Anticancer
25.8

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.