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Peptide record

TPDB92131

L10 Antibacterial Anticancer Cell-penetrating Peptides Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92131
L10
Antibacterial Anticancer Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
DILIIVGGKRRR-NH2
Physicochemical Analysis
C61H114N22O15
ANCEQHMFPSTWY
RI
1395.71
12.12
4
1
5
+3
3.25
-0.017
154.17
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
3
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
3
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C61H114N22O15
1395.71
12.12
+3
3.25
-0.017
Amidation
L
Cationic
Linear
Free
N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

RAW 264.7 And Infected With S. Agalactiae H93

Assay & Model

Female ICR mice
Female ICR mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
FITC dye
Vacuole
Cell internalization ratio reached 43.4%
Macropinocytosis
In vitro and in vivo
CCCCCGGGCCSSSCCC
Additional Detail Fields 1 fields
CCCCCGGGCCSSSCCC