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Peptide record

TPDB92120

CPP-PNA Antibacterial Antifungal Cell-penetrating Peptides Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB92120
CPP-PNA
Antibacterial Antifungal Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD-MOD CPPsite3.0 MLCPP 2.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Conjugation with nucleic acid Chemical: Nucleic acid is attached via an ethylene glyol linker
Sequence
KFFKFFKFFK
Physicochemical Analysis
C78H104N14O11
ARNDCEQGHILMPSTWYV
F
1413.77
11.00
4
0
6
+4
-2.82
0.120
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
6
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 6 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C78H104N14O11
1413.77
11.00
+4
-2.82
0.120
Conjugation with nucleic acid
Nucleic acid is attached via an ethylene glyol linker
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

J774A.1

Assay & Model

Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308
Brucella suis 1330, B. melitensis 16M and Brucella abortus 2308

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
PNA
In vitro and in vivo
CCHHHHTTCC
Additional Detail Fields 1 fields
CCHHHHTTCC