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Peptide record

TPDB92111

Human Beta Defensin- Antibacterial Anticancer Antifungal Antiparasitic Antiviral Blood-Brain Barrier Toxicity standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB92111
Human Beta Defensin-
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Blood-Brain Barrier Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb dbAMP 3.0 i2APP AI4AVP AVPpred-BWR DRAVP 2.0 BBPpredict
standard
No
A 41-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Chemical: Cys8-Cys37, Cys15-Cys30, Cys20-Cys38
Sequence
GIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
Physicochemical Analysis
C188H311N55O50S6
NEMW
CG
4334.24
9.24
8
1
10
+6
6.61
-0.102
64.15
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
43.03
12
Residue Composition
number
1
A
2
R
0
N
1
D
6
C
0
E
1
Q
6
G
1
H
3
I
2
L
5
K
0
M
1
F
5
P
1
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 6 E: 0 Q: 1 G: 6 H: 1 I: 3 L: 2 K: 5 M: 0 F: 1 P: 5 S: 1 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
41
C188H311N55O50S6
4334.24
9.24
+6
6.61
-0.102
Cys8-Cys37, Cys15-Cys30, Cys20-Cys38
Linear
Similarity
Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro
[H]NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H]3CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC1=O)[C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CSSC[C@H](NC2=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N3)[C@@H](C)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier

Assay & Model

Origin/Source

Source & Reference

NA
B3Pdb

Other

Chemically synthesized