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Peptide record

TPDB92110

PACAP38 Antibacterial Anticancer Antifungal Neuropeptide Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB92110
PACAP38
Antibacterial Anticancer Antifungal Neuropeptide Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Neuroactive peptides
AntiBP3 Peptipedia CancerPPD 2.0 dbACP CAFPdb dbAMP
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
HSDGIFTDSYSRYRKQMAVKKYLAAVLGRRYRQRFRNK-NH2
Physicochemical Analysis
C207H330N68O54S1
CEPW
R
4667.38
11.40
12
2
15
+9
7.13
-1.145
53.95
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
5960
127.69
11
Residue Composition
number
3
A
7
R
1
N
2
D
0
C
0
E
2
Q
2
G
1
H
1
I
2
L
4
K
1
M
2
F
0
P
3
S
1
T
0
W
4
Y
2
V
Amino Acid Distribution
A: 3 R: 7 N: 1 D: 2 C: 0 E: 0 Q: 2 G: 2 H: 1 I: 1 L: 2 K: 4 M: 1 F: 2 P: 0 S: 3 T: 1 W: 0 Y: 4 V: 2
Chemical Descriptors
38
C207H330N68O54S1
4667.38
11.40
+9
7.13
-1.145
Amidation
L
Linear
Free
Antimicrobial and Anticancer
Clarias gariepinus
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50=14.97± 1.16 µM
Anticancer
14.97

Target

Lung Cancer
H-460
Lung

Assay & Model

Crystal Violet assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.