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Peptide record

TPDB92101

F3 Antibacterial Anticancer Antifungal Tumor-homing Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB92101
F3
Antibacterial Anticancer Antifungal Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
N-terminal: Addition of extra Cys on the N-terminal
Sequence
KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
Physicochemical Analysis
C152H263N49O41
NCGHIMFTWYV
KP
3433.06
11.26
11
3
6
+8
18.65
-1.945
28.71
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
5
A
3
R
0
N
1
D
0
C
2
E
1
Q
0
G
0
H
0
I
1
L
8
K
0
M
0
F
8
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 3 N: 0 D: 1 C: 0 E: 2 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 8 M: 0 F: 0 P: 8 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
31
C152H263N49O41
3433.06
11.26
+8
18.65
-1.945
Addition of extra Cys on the N-terminal
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell and tumor cell
Homing
Breast cancer ,Fibrosarcoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting
2009
Park JH et al. Small. 2009 Mar 5(6):694-700.
US 7,544,767 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Mice bearing human (MDA-MB-435 human carcinoma and HT1080 human fibrosarcoma) xenograft
Synthetic
Superparamagnetic nanospheres, superparamagnetic IO nanoworms (NWs)
Additional Detail Fields 2 fields
Superparamagnetic nanospheres, superparamagnetic IO nanoworms (NWs)
Mice bearing human (MDA-MB-435 human carcinoma and HT1080 human fibrosarcoma) xenograft