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Peptide record

TPDB92100

F3 Antibacterial Anticancer Antifungal Tumor-homing Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB92100
F3
Antibacterial Anticancer Antifungal Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
C-terminal: Cysteine
Sequence
KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
Physicochemical Analysis
C152H263N49O41
NCGHIMFTWYV
KP
3433.06
11.26
11
3
6
+8
18.65
-1.945
28.71
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
5
A
3
R
0
N
1
D
0
C
2
E
1
Q
0
G
0
H
0
I
1
L
8
K
0
M
0
F
8
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 3 N: 0 D: 1 C: 0 E: 2 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 8 M: 0 F: 0 P: 8 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
31
C152H263N49O41
3433.06
11.26
+8
18.65
-1.945
Cysteine
CendR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Homing
Triple-negative Breast cancer
Nucleolin

Source & Reference

TumorHoPe2.0
TumorHoPe2
A positron emission tomography image-guidable unimolecular micelle nanoplatform for cancer theranostic applications
2018
Jia Yang et al. Acta Biomater. 2018 Oct 1:79:306-316.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231 breast cancer cells, L929 fibroblasts
female nude mice
Synthetic
PAMAM-based micelles, Doxorubicin (DOX), 64Cu for PET imaging
Additional Detail Fields 3 fields
PAMAM-based micelles, Doxorubicin (DOX), 64Cu for PET imaging
MDA-MB-231 breast cancer cells, L929 fibroblasts
female nude mice