Back to search

Peptide record

TPDB92096

Mela3 Antibacterial Anticancer Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92096
Mela3
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
GKPICGETCFKGKCYTPGCTCSYPICKKD
Physicochemical Analysis
C134H212N34O40S6
ARNQHLMWV
C
3131.72
8.30
5
2
5
+3
5.07
-0.400
26.90
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
107.13
12
Residue Composition
number
0
A
0
R
0
N
1
D
6
C
1
E
0
Q
4
G
0
H
2
I
0
L
5
K
0
M
1
F
3
P
1
S
3
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 6 E: 1 Q: 0 G: 4 H: 0 I: 2 L: 0 K: 5 M: 0 F: 1 P: 3 S: 1 T: 3 W: 0 Y: 2 V: 0
Chemical Descriptors
29
C134H212N34O40S6
3131.72
8.30
+3
5.07
-0.400
Cyclized
L
Cyclic
Cyclized
Antibacterial and Anticancer
Melicytus latifolius
Evidence Records 2 records
Evidence 1 Activity

Activity

CC50
CC50 = 2.04 ±0.26 µM
Anticancer
2.04

Target

Skin Cancer
MM96L
Skin

Assay & Model

Resazurin dye assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

CC50
CC50 = 18.73 ±1.82 µM
Anticancer
18.73

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

Resazurin dye assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2015