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Peptide record

TPDB92091

DRS-DU-1 Antibacterial Anticancer Antifungal Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB92091
DRS-DU-1
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 dbACP Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
ALWKSLLKNVGKAAGKAALNAVTDMVNQ-NH2
Physicochemical Analysis
C129H219N37O37S1
RCEHIFPY
A
2912.44
10.55
4
1
15
+3
2.19
0.150
108.21
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
188.84
6
Residue Composition
number
6
A
0
R
3
N
1
D
0
C
0
E
1
Q
2
G
0
H
0
I
4
L
4
K
1
M
0
F
0
P
1
S
1
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 6 R: 0 N: 3 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 4 K: 4 M: 1 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 3
Chemical Descriptors
28
C129H219N37O37S1
2912.44
10.55
+3
2.19
0.150
Amidation
L
Linear
Free
Antimicrobial and Anticancer
Callimedusa (Phyllomedusa) duellmani
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 8.43 µM
Anticancer
8.43 µM

Target

Lung Cancer
H-157
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 21.6 µM
Anticancer
21.6 µM

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018