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Peptide record

TPDB92086

NRC-03 Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB92086
NRC-03
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GRRKRKWLRRIGKGVKIIGGAALDHL-NH2
Physicochemical Analysis
C132H232N48O29
NCEQMFPSTY
RG
2955.60
12.59
10
1
10
+8
5.52
-0.577
108.85
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
186.09
0
Residue Composition
number
2
A
5
R
0
N
1
D
0
C
0
E
0
Q
5
G
1
H
3
I
3
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 5 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 5 H: 1 I: 3 L: 3 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C132H232N48O29
2955.60
12.59
+8
5.52
-0.577
Amidation
L
Linear
Free
Antimicrobial
skin mucous secretions of winter flounder
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 45 µg/ml
Anticancer
45 µg/mL

Target

Oral Cancer
CAL-27
Tongue

Assay & Model

CCK-8 assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 45 µg/ml
Anticancer
45 µg/mL

Target

Oral Cancer
SCC-9
Tongue

Assay & Model

CCK-8 assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2022