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Peptide record

TPDB92080

Peptide P Antibacterial Anticancer Antifungal Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB92080
Peptide P
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept CAFPdb
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-KWKSFLKTFKSLKKTVLHTLLKAISS-NH2
Physicochemical Analysis
C145H242N36O34
RNDCEQGMPY
K
3033.74
11.29
8
0
11
+7
1.51
-0.062
105.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
181.29
7
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
5
L
7
K
0
M
2
F
0
P
4
S
3
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 5 K: 7 M: 0 F: 2 P: 0 S: 4 T: 3 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C145H242N36O34
3033.74
11.29
+7
1.51
-0.062
Amidation
L
Linear
Acetylation
Anticancer
A12L/A20L
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50= 1.71±0.07 µMol/L
Anticancer
1.71

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT/MTS assay
1-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2012

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.