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Peptide record

TPDB92073

Bombinin-BO1 Antibacterial Anticancer Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB92073
Bombinin-BO1
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia CancerPPD 2.0 dbACP Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIGSAILSAGKSIIKGLAKGLAEHF-NH2
Physicochemical Analysis
C111H188N30O31
RNDCQMPTWYV
G
2438.90
10.32
4
1
12
+2
1.66
0.664
125.20
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
1
E
0
Q
5
G
1
H
4
I
3
L
3
K
0
M
1
F
0
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 1 I: 4 L: 3 K: 3 M: 0 F: 1 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C111H188N30O31
2438.90
10.32
+2
1.66
0.664
Amidation
L
Linear
Free
Antimicrobial
Bombina orientalis
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 0.76 µM
Anticancer
0.76 µM

Target

Liver Cancer
SK-HEP-1
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 3.75 µM
Anticancer
3.75 µM

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018
Evidence 3 Activity

Activity

IC50
IC50 = 3.91 µM
Anticancer
3.91 µM

Target

Liver Cancer
Huh-7
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018