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Peptide record

TPDB92051

TAT-RasGAP317-326 Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB92051
TAT-RasGAP317-326
Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept CAFPdb dbAMP CPPsite3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
N-terminal: Conjugated with FITC or TMR
Sequence
GRKKRRQRRRGGWMWVTNLRTD
Physicochemical Analysis
C119H201N49O29S1
ACEHIFPSY
R
2814.28
12.80
9
1
5
+8
5.77
-2.014
30.91
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
390.86
4
Residue Composition
number
0
A
7
R
1
N
1
D
0
C
0
E
1
Q
3
G
0
H
0
I
1
L
2
K
1
M
0
F
0
P
0
S
2
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 7 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 1 K: 2 M: 1 F: 0 P: 0 S: 0 T: 2 W: 2 Y: 0 V: 1
Chemical Descriptors
22
C119H201N49O29S1
2814.28
12.80
+8
5.77
-2.014
Free
Retro-inverso (D)
Linear
Conjugated with FITC or TMR
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells (wild type and KCNN4 KO)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear Retro-inverso (D)
Chimeric
FITC and TMR dye
Endocytosis
In vitro
CCCCCCTTCC
Additional Detail Fields 1 fields
CCCCCCTTCC