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Peptide record

TPDB92048

Fi-Histin1-21 Antibacterial Anticancer Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB92048
Fi-Histin1-21
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-SRSSRAGLQFPVGRIHRLLRK-NH2
Physicochemical Analysis
C106H184N40O26
NDCEMTWY
R
2434.88
13.00
7
0
7
+6
4.22
-0.629
92.86
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
1
Q
2
G
1
H
1
I
3
L
1
K
0
M
1
F
1
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 1 L: 3 K: 1 M: 0 F: 1 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
21
C106H184N40O26
2434.88
13.00
+6
4.22
-0.629
Amidation
L
Linear
Acetylation
Antimicrobial
Fenneropenaeus indicus
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 22.670 ± 13.939 µM
Anticancer
22.670

Target

Lung Cancer
NCI-H-460
Lung

Assay & Model

XTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 31.274 ± 24.531 µM
Anticancer
31.274

Target

Liver Cancer
Hep-2
Liver

Assay & Model

XTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019