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Peptide record

TPDB91993

MSI-103 Antibacterial Cell-penetrating Peptides Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB91993
MSI-103
Antibacterial Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia CPPsite3.0 PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Fluka 630 Red-Labeled
Sequence
KIAGKIAKIAGKIAKIAGKIA-NH2
Physicochemical Analysis
C96H179N27O22
RNDCEQHLMFPSTWYV
AIK
2063.64
11.21
6
0
12
+6
3.09
0.629
140.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
6
I
0
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 6 L: 0 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C96H179N27O22
2063.64
11.21
+6
3.09
0.629
Amidation
L
Amphiphilic
Linear
Fluka 630 Red-Labeled
N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Synthetic
Fluka 630 Red dye
Showed endocytotic cell uptake with a similar efficiency as PGLa and MAG2
Endocytosis
In vitro
CBSSCSSTTSHHHHHSSSCBC
Additional Detail Fields 1 fields
CBSSCSSTTSHHHHHSSSCBC