Peptide record

TPDB91992

Kassiniatuerin-3 Antibacterial Anticancer Antifungal Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB91992
Kassiniatuerin-3
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 dbACP AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FIQHLIPLIPHAIQGIKDIF-NH2
Physicochemical Analysis
C113H177N27O25
RNCEMSTWYV
I
2313.81
7.97
3
1
11
+0
0.80
0.880
161.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
2
Q
1
G
2
H
6
I
2
L
1
K
0
M
2
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 2 G: 1 H: 2 I: 6 L: 2 K: 1 M: 0 F: 2 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C113H177N27O25
2313.81
7.97
+0
0.80
0.880
Amidation
L
Linear
Free
Antimicrobial and Anticancer
Kassina senegalensis
Evidence Records 6 records
Evidence 1 Activity

Activity

IC50
IC50 = 13.20 µM
Anticancer
13.20 µM

Target

Brain Tumor
U251-MG
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 3.79 µM
Anticancer
3.79 µM

Target

Prostate Cancer
LNCaP
Prostate

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020
Evidence 3 Activity

Activity

IC50
IC50 = 10.03 µM
Anticancer
10.03 µM

Target

Lung Cancer
H-838
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020
Evidence 4 Activity

Activity

IC50
IC50 = 1.67 µM
Anticancer
1.67 µM

Target

Lung Cancer
H-460
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020
Evidence 5 Activity

Activity

IC50
IC50 = 21.54 µM
Anticancer
21.54 µM

Target

Lung Cancer
H-157
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020
Evidence 6 Activity

Activity

IC50
IC50 = 4.52 µM
Anticancer
4.52 µM

Target

Lung Cancer
NCI-H23
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020