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Peptide record

TPDB91979

T-Oncocin Antibacterial Anticancer Blood-Brain Barrier Cell-penetrating Peptides Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB91979
T-Oncocin
Antibacterial Anticancer Blood-Brain Barrier Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia B3Pred BBPpredict CPPsite3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Blood-Brain Barrier, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with TAMRA
Sequence
VDKPPYLPRPRPPRRIYNR-NH2
Physicochemical Analysis
C109H176N36O25
ACEQGHMFSTW
P
2390.82
11.84
6
1
5
+5
6.71
-1.742
56.32
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
2980
124.64
3
Residue Composition
number
0
A
5
R
1
N
1
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
6
P
0
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 6 S: 0 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
19
C109H176N36O25
2390.82
11.84
+5
6.71
-1.742
Amidation
L
Cationic
Linear
Conjugated with TAMRA
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

bEnd.3 and Bioni-010c cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
TAMRA dye and 14C-mannitol
Lesser extent of internalization than T-Tat47–57 and T-penetratin
Endocytosis
In vitro