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Peptide record

TPDB91976

Phylloseptin-PTa Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB91976
Phylloseptin-PTa
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 dbACP CAFPdb dbAMP Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLSLIPKIAGGIAALAKHL-NH2
Physicochemical Analysis
C93H157N23O21
RNDCEQMTWYV
AL
1933.41
10.60
3
0
12
+2
-1.44
1.289
164.74
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
3
I
4
L
2
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 3 L: 4 K: 2 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C93H157N23O21
1933.41
10.60
+2
-1.44
1.289
Amidation
L
Linear
Free
Antimicrobial and Anticancer
Phyllomedusa tarsius
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 6.73 µM
Anticancer
6.73 µM

Target

Lung Cancer
NCI-H-157
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.