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Peptide record

TPDB91975

Phylloseptin-PHa Antibacterial Anticancer Antifungal Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB91975
Phylloseptin-PHa
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 dbACP Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLSLIPAAISAVSALANHF-NH2
Physicochemical Analysis
C92H144N22O24
RDCEQGKMTWY
A
1942.29
7.85
1
0
13
+0
-3.12
1.500
144.21
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
1
H
2
I
3
L
0
K
0
M
2
F
1
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 3 K: 0 M: 0 F: 2 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C92H144N22O24
1942.29
7.85
+0
-3.12
1.500
Amidation
L
Linear
Free
Antimicrobial and Anticancer
Pithecopus hypochondrialis
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 14.10 µM
Anticancer
14.10 µM

Target

Lung Cancer
NCI-H-157
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.