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Peptide record

TPDB91953

pVec Antibacterial Antifungal Antiparasitic Blood-Brain Barrier Cell-penetrating Peptides Toxicity Tumor-homing Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB91953
pVec
Antibacterial Antifungal Antiparasitic Blood-Brain Barrier Cell-penetrating Peptides Toxicity Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP i2APP B3Pred BBPpredict CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP TumorHoPe2.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
C-terminal: ASO-1 Conjugated
Sequence
LLIILRRRIRKQAHAHSK
Physicochemical Analysis
C98H177N37O21
NDCEGMFPTWYV
R
2209.72
12.88
8
0
8
+6
4.90
-0.444
141.11
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
1
Q
0
G
2
H
3
I
3
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 2 I: 3 L: 3 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C98H177N37O21
2209.72
12.88
+6
4.90
-0.444
ASO-1 Conjugated
L
Amphipathic
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S. Aureus Strain Atcc 25923, E. Coli Strain K12, And L. Monocytogenes Strain And A549 Cell Line

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Antisense oligonucleotide (ASO) targeting SAM-1
Efficient delivery of ASO-1 into the bacterial cell.
In vitro
CCTTTHHHHHHHHHHHHHHHSCC
Additional Detail Fields 1 fields
CCTTTHHHHHHHHHHHHHHHSCC