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Peptide record

TPDB91950

peptide 20 Antibacterial Cell-penetrating Peptides Hemolysis standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB91950
peptide 20
Antibacterial Cell-penetrating Peptides Hemolysis
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, and Hemolysis) peptide sequence curated from AntiBP3, Peptipedia, CellPPD, and other sources, with an available 3D structural model.
N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
KLALKLALKAWKAALKLA
Physicochemical Analysis
C95H168N24O19
RNDCEQGHIMFPSTYV
AL
1950.53
11.12
5
0
13
+5
-1.28
0.733
163.33
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
281.97
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
5
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C95H168N24O19
1950.53
11.12
+5
-1.28
0.733
Free
L
Amphipathic
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
5(6)-carboxyfluorescein (FAM) dye
309.34 RFU
In vitro
CTHHHHHHHHHHHHTTTTTC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHHTTTTTC